On a December day a few years ago, John Horton Conway settled in for an interview at the office of neuroscientist Sandra Witelson. Conway wasn’t there for an appointment proper, but rather to provide fodder for Witelson’s ongoing research on scientifically minded brains. All the same, he’d braced himself for an arsenal of standard neuropsychological assessments, and custom tests designed to capture his brain performing live during a functional MRI.
Witelson tried to reassure her subject, explaining what she was after with the tests. “With imaging, one can look at the microscopic anatomy of the brain, just through a picture,” she said. “So what I’m hoping is that these tests will get at different types of mathematics, and we will be able to see different parts of your brain light up when you’re thinking in different ways. We want to see which part of your brain is particularly active when you’re thinking some of your great mathematical thoughts.”
“Well, you know, I’m not sure that I can have great mathematical thoughts to order,” said Conway. “I can have lesser thoughts.”
“That’ll do,” said Witelson.







