Avastin and the Power of Hope

This week, an FDA panel unanimously voted to revoke its approval of Avastin (bevacizumab) for breast cancer. The decision evoked cheers from some groups and jeers from others.  At least one group derided the decision as the work of a  “death panel.” Initially hailed as a wonder drug, Avastin is a monoclonal antibody first approved […]

A Royal Pain

A lovely young English couple are planning to visit my town in a fortnight, along with 70-odd out-of-town police officers, trucks-full of barricades and a personal hair stylist. As William and Kate’s arrival approaches, I find myself situated as a public servant, so I shan’t venture any opinion at all on Canada’s future with the […]

Delectable Dirt

Kids will put anything in their mouths. My aunt, who lived briefly in Hawaii, once found my cousin gnawing on a dead lizard. My childhood tastes were less exotic. I loved dirt. Eating dirt was forbidden. I was old enough to understand that. But I could. not. help. myself. My mother would often find me […]

Autism’s Plot

Erika wants to know about the state of autism research. “How is the field doing in terms of rigorous science?” she asks. “What is the most promising theory about how autism develops?” The first question’s easy to answer: pretty damn well. In 2008 (the last time a good survey was done), autism research reaped $144 […]

Diagnosing Grief

Last week Jessa wrote about psychiatric diagnoses moving from the quantum to the continuum, from neat little packages to subtleties that include shades of gray and something called “a quantifiable baseline of life functioning.”  The same week, Ginny published a story about the same diagnostic changes but applied specifically to pathological grief – the problem […]

Psychiatry Comes of Age

Whenever one paradigm gives way to another in science, the transition is traumatic. Hard-earned knowledge from the earlier perspective cannot be meaningfully compared with new research in the next paradigm, because even the language of the new scientific generation is slightly different. Information is lost or devalued. Such is the price of progress. The coming […]

Why Circumcision Protects Against HIV

On LWON’s first birthday, Richard Panek asked me to explain why being circumcised makes a man less likely to catch HIV. So I will. Here you go, Richard. Let’s be honest. Foreskin is weird. The rules of evolution suggest that it once conferred an advantage, but I can’t fathom what that advantage might have been. […]

The Stuff of Hot

Late Saturday evening, I was cutting jalapeños for the salsa for the next day’s barbeque party. I had a few other things on my mind — like my bean salad, and cleaning the bathroom, and figuring out what to write for this post — and so I forgot the lesson learned the last time I […]